Toll-Like Receptor 9 Enhances Nephritogenic Immunity and Glomerular Leukocyte Recruitment, Exacerbating Experimental Crescentic Glomerulonephritis

Glomerular disease can be triggered or exacerbated by microbes that activate the immune system by Toll-like receptor (TLR) ligation. TLR9 activation promotes host defenses through the enhancement of innate and adaptive immune responses that facilitate the recruitment of leukocytes to areas of inflam...

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Autors principals: Summers, Shaun A., Steinmetz, Oliver M., Ooi, Joshua D., Gan, Poh-yi, O'Sullivan, Kim M., Visvanathan, Kumar, Akira, Shizuo, Kitching, A. Richard, Holdsworth, Stephen R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966783/
https://ncbi.nlm.nih.gov/pubmed/20847283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100153
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