The Th17-Defining Transcription Factor RORγt Promotes Glomerulonephritis

Although Th17 responses may contribute to the pathogenesis of glomerulonephritis, whether the key transcription factor in Th17 cell development, RORγt, also promotes glomerulonephritis is unknown. Here, we induced crescentic glomerulonephritis in wild-type and RORγt-deficient (RORγt(−/−)) mice. RORγ...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Steinmetz, Oliver M., Summers, Shaun A., Gan, Poh-Yi, Semple, Timothy, Holdsworth, Stephen R., Kitching, A. Richard
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Nephrology 2011
विषय:
Basic Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060441/
https://ncbi.nlm.nih.gov/pubmed/21183590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010040435
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