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Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells
The molecular mechanisms underlying the differentiation of interleukin 17–producing T helper cells (T(H)-17 cells) are still poorly understood. Here we show that optimal transcription of the gene encoding interleukin 17 (Il17) required a 2-kilobase promoter and at least one conserved noncoding (enha...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Immunol |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778724/ https://ncbi.nlm.nih.gov/pubmed/18849990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1663 |
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