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Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation
Ataxia-telangiectasia mutated (ATM) is needed for the initiation of the double-strand break (DSB) repair by homologous recombination (HR). ATM triggers DSB end resection by stimulating the nucleolytic activity of CtIP and MRE11 to generate 3′-ssDNA overhangs, followed by RPA loading and RAD51 nucleo...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381069/ https://ncbi.nlm.nih.gov/pubmed/25753674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv160 |
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