Roles of Rad51 paralogs for promoting homologous recombination in Leishmania infantum

To achieve drug resistance Leishmania parasite alters gene copy number by using its repeated sequences widely distributed through the genome. Even though homologous recombination (HR) is ascribed to maintain genome stability, this eukaryote exploits this potent mechanism driven by the Rad51 recombin...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Genois, Marie-Michelle, Plourde, Marie, Éthier, Chantal, Roy, Gaétan, Poirier, Guy G., Ouellette, Marc, Masson, Jean-Yves
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357719/
https://ncbi.nlm.nih.gov/pubmed/25712090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv118
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