Roles of Rad51 paralogs for promoting homologous recombination in Leishmania infantum

To achieve drug resistance Leishmania parasite alters gene copy number by using its repeated sequences widely distributed through the genome. Even though homologous recombination (HR) is ascribed to maintain genome stability, this eukaryote exploits this potent mechanism driven by the Rad51 recombin...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Genois, Marie-Michelle, Plourde, Marie, Éthier, Chantal, Roy, Gaétan, Poirier, Guy G., Ouellette, Marc, Masson, Jean-Yves
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Genome Integrity, Repair and Replication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357719/
https://ncbi.nlm.nih.gov/pubmed/25712090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv118
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