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The Rad51 paralog complex Rad55-Rad57 acts as a molecular chaperone during homologous recombination

Homologous recombination (HR) is essential for maintenance of genome integrity. Rad51 paralogs fulfill a conserved but undefined role in HR, and their mutations are associated with increased cancer risk in humans. Here, we use single-molecule imaging to reveal that the Saccharomyces cerevisiae Rad51...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Roy, Upasana, Kwon, Youngho, Marie, Lea, Symington, Lorraine, Sung, Patrick, Lisby, Michael, Greene, Eric C.
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262405/
https://ncbi.nlm.nih.gov/pubmed/33421364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.12.019
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