Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation

Ataxia-telangiectasia mutated (ATM) is needed for the initiation of the double-strand break (DSB) repair by homologous recombination (HR). ATM triggers DSB end resection by stimulating the nucleolytic activity of CtIP and MRE11 to generate 3′-ssDNA overhangs, followed by RPA loading and RAD51 nucleo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Bakr, A., Oing, C., Köcher, S., Borgmann, K., Dornreiter, I., Petersen, C., Dikomey, E., Mansour, W.Y.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381069/
https://ncbi.nlm.nih.gov/pubmed/25753674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv160
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker