Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase

Double-strand breaks (DSBs) are repaired by two distinct pathways, non-homologous end joining (NHEJ) and homologous recombination (HR). The endonuclease Artemis and the PIK kinase Ataxia-Telangiectasia Mutated (ATM), mutated in prominent human radiosensitivity syndromes, are essential for repairing...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Köcher, Sabrina, Rieckmann, Thorsten, Rohaly, Gabor, Mansour, Wael Y., Dikomey, Ekkehard, Dornreiter, Irena, Dahm-Daphi, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458552/
https://ncbi.nlm.nih.gov/pubmed/22730303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks604
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados