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Integration of Shallow Gradients of Shh and Netrin-1 Guides Commissural Axons
During nervous system development, gradients of Sonic Hedgehog (Shh) and Netrin-1 attract growth cones of commissural axons toward the floor plate of the embryonic spinal cord. Mice defective for either Shh or Netrin-1 signaling have commissural axon guidance defects, suggesting that both Shh and Ne...
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| Publicado en: | PLoS Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4380419/ https://ncbi.nlm.nih.gov/pubmed/25826604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002119 |
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