Structural basis for misfolding in myocilin-associated glaucoma

Olfactomedin (OLF) domain-containing proteins play roles in fundamental cellular processes and have been implicated in disorders ranging from glaucoma, cancers and inflammatory bowel disorder, to attention deficit disorder and childhood obesity. We solved crystal structures of the OLF domain of myoc...

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Vydáno v:Hum Mol Genet
Hlavní autoři: Donegan, Rebecca K., Hill, Shannon E., Freeman, Dana M., Nguyen, Elaine, Orwig, Susan D., Turnage, Katherine C., Lieberman, Raquel L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380063/
https://ncbi.nlm.nih.gov/pubmed/25524706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu730
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