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Ligands for glaucoma-associated myocilin discovered by a generic binding assay
Mutations in the olfactomedin domain of myocilin (myoc-OLF) are the strongest link to inherited primary open angle glaucoma. In this recently-identified protein misfolding disorder, aggregation-prone disease variants of myocilin hasten glaucoma-associated elevation of intraocular pressure, leading t...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944078/ https://ncbi.nlm.nih.gov/pubmed/24279319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4007776 |
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