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Structure and misfolding of the flexible tripartite coiled-coil domain of glaucoma-associated myocilin
Glaucoma-associated myocilin is a member of the olfactomedins, a protein family involved in neuronal development and human diseases. Molecular studies of the myocilin N-terminal coiled-coils demonstrate a unique tripartite architecture: a Y-shaped parallel dimer-of-dimers with distinct tetramer and...
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| Pubblicato in: | Structure |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5685557/ https://ncbi.nlm.nih.gov/pubmed/29056483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.09.008 |
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