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Structure and misfolding of the flexible tripartite coiled-coil domain of glaucoma-associated myocilin

Glaucoma-associated myocilin is a member of the olfactomedins, a protein family involved in neuronal development and human diseases. Molecular studies of the myocilin N-terminal coiled-coils demonstrate a unique tripartite architecture: a Y-shaped parallel dimer-of-dimers with distinct tetramer and...

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Podrobná bibliografie
Vydáno v:Structure
Hlavní autoři: Hill, Shannon E., Nguyen, Elaine, Donegan, Rebecca K., Patterson-Orazem, Athéna C., Hazel, Anthony, Gumbart, James C., Lieberman, Raquel L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685557/
https://ncbi.nlm.nih.gov/pubmed/29056483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.09.008
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