Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma

BACKGROUND: Melanoma is the most fatal skin cancer displaying a high degree of molecular heterogeneity. Phenotype switching is a mechanism that contributes to melanoma heterogeneity by altering transcription profiles for the transition between states of proliferation/differentiation and invasion/ste...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Biol
Prif Awduron: Cheng, Phil F, Shakhova, Olga, Widmer, Daniel S, Eichhoff, Ossia M, Zingg, Daniel, Frommel, Sandra C, Belloni, Benedetta, Raaijmakers, Marieke IG, Goldinger, Simone M, Santoro, Raffaella, Hemmi, Silvio, Sommer, Lukas, Dummer, Reinhard, Levesque, Mitchell P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378455/
https://ncbi.nlm.nih.gov/pubmed/25885555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0594-4
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg