SMAD signaling promotes melanoma metastasis independently of phenotype switching

The development of metastatic melanoma is thought to require the dynamic shifting of neoplastic cells between proliferative and invasive phenotypes. Contrary to this conventional “phenotype switching” model, we now show that disease progression can involve malignant melanoma cells simultaneously dis...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Tuncer, Eylul, Calçada, Raquel R., Zingg, Daniel, Varum, Sandra, Cheng, Phil, Freiberger, Sandra N., Deng, Chu-Xia, Kleiter, Ingo, Levesque, Mitchell P., Dummer, Reinhard, Sommer, Lukas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597210/
https://ncbi.nlm.nih.gov/pubmed/31039140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94295
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