SMAD signaling promotes melanoma metastasis independently of phenotype switching

The development of metastatic melanoma is thought to require the dynamic shifting of neoplastic cells between proliferative and invasive phenotypes. Contrary to this conventional “phenotype switching” model, we now show that disease progression can involve malignant melanoma cells simultaneously dis...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Tuncer, Eylul, Calçada, Raquel R., Zingg, Daniel, Varum, Sandra, Cheng, Phil, Freiberger, Sandra N., Deng, Chu-Xia, Kleiter, Ingo, Levesque, Mitchell P., Dummer, Reinhard, Sommer, Lukas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597210/
https://ncbi.nlm.nih.gov/pubmed/31039140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94295
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