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Prolonged Proteasome Inhibition Cyclically Upregulates Oct3/4 and Nanog Gene Expression, but Reduces Induced Pluripotent Stem Cell Colony Formation

There is ample evidence that the ubiquitin–proteasome system is an important regulator of transcription and its activity is necessary for maintaining pluripotency and promoting cellular reprogramming. Moreover, proteasome activity contributes to maintaining the open chromatin structure found in plur...

詳細記述

保存先:
書誌詳細
出版年:Cell Reprogram
主要な著者: Floyd, Elizabeth Z., Staszkiewicz, Jaroslaw, Power, Rachel A., Kilroy, Gail, Kirk-Ballard, Heather, Barnes, Christian W., Strickler, Karen L., Rim, Jong S., Harkins, Lettie L., Gao, Ru, Kim, Jeong, Eilertsen, Kenneth J.
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378358/
https://ncbi.nlm.nih.gov/pubmed/25826722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2014.0030
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