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Nocodazole Treatment Decreases Expression of Pluripotency Markers Nanog and Oct4 in Human Embryonic Stem Cells

Nocodazole is a known destabiliser of microtubule dynamics and arrests cell-cycle at the G2/M phase. In the context of the human embryonic stem cell (hESC) it is important to understand how this arrest influences the pluripotency of cells. Here we report for the first time the changes in the express...

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Autori principali: Kallas, Ade, Pook, Martin, Maimets, Martti, Zimmermann, Külli, Maimets, Toivo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084750/
https://ncbi.nlm.nih.gov/pubmed/21559451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019114
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