Silencing Histone Deacetylase–Specific Isoforms Enhances Expression of Pluripotency Genes in Bovine Fibroblasts

Histone deacetylases (HDACs) catalyze deacetylation of histones that results in altered transcriptional activity. Inhibitors of HDACs have been shown to induce transcriptional changes that contribute positively to reprogramming somatic cells either by nuclear transfer or inducing a pluripotent state...

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Autori principali: Staszkiewicz, Jaroslaw, Power, Rachel A., Harkins, Lettie L., Barnes, Christian W., Strickler, Karen L., Rim, Jong S., Bondioli, Kenneth R., Eilersten, Kenneth J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2013
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Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787336/
https://ncbi.nlm.nih.gov/pubmed/24020699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2013.0026
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