Silencing Histone Deacetylase–Specific Isoforms Enhances Expression of Pluripotency Genes in Bovine Fibroblasts

Histone deacetylases (HDACs) catalyze deacetylation of histones that results in altered transcriptional activity. Inhibitors of HDACs have been shown to induce transcriptional changes that contribute positively to reprogramming somatic cells either by nuclear transfer or inducing a pluripotent state...

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Detalhes bibliográficos
Main Authors: Staszkiewicz, Jaroslaw, Power, Rachel A., Harkins, Lettie L., Barnes, Christian W., Strickler, Karen L., Rim, Jong S., Bondioli, Kenneth R., Eilersten, Kenneth J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787336/
https://ncbi.nlm.nih.gov/pubmed/24020699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2013.0026
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