Hypokalaemia induces Ca(2+) overload and Ca(2+) waves in ventricular myocytes by reducing Na(+),K(+)-ATPase α(2) activity

Hypokalaemia is a risk factor for development of ventricular arrhythmias. The aim of this study was to determine the cellular mechanisms leading to triggering of arrhythmias in ventricular myocytes exposed to low K(o). Low K(o), corresponding to moderate hypokalaemia, increased Ca(2+) transient ampl...

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Foilsithe in:J Physiol
Main Authors: Aronsen, J M, Skogestad, J, Lewalle, A, Louch, W E, Hougen, K, Stokke, M K, Swift, F, Niederer, S, Smith, N P, Sejersted, O M, Sjaastad, I
Formáid: Artigo
Teanga:Inglês
Foilsithe: BlackWell Publishing Ltd 2015
Ábhair:
Research Papers
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376427/
https://ncbi.nlm.nih.gov/pubmed/25772299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.279893
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