Hypokalaemia induces Ca(2+) overload and Ca(2+) waves in ventricular myocytes by reducing Na(+),K(+)-ATPase α(2) activity

Hypokalaemia is a risk factor for development of ventricular arrhythmias. The aim of this study was to determine the cellular mechanisms leading to triggering of arrhythmias in ventricular myocytes exposed to low K(o). Low K(o), corresponding to moderate hypokalaemia, increased Ca(2+) transient ampl...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Physiol
Hlavní autoři: Aronsen, J M, Skogestad, J, Lewalle, A, Louch, W E, Hougen, K, Stokke, M K, Swift, F, Niederer, S, Smith, N P, Sejersted, O M, Sjaastad, I
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376427/
https://ncbi.nlm.nih.gov/pubmed/25772299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.279893
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky