Beta-Adrenoceptor Stimulation Reveals Ca(2+) Waves and Sarcoplasmic Reticulum Ca(2+) Depletion in Left Ventricular Cardiomyocytes from Post-Infarction Rats with and without Heart Failure

Abnormal cellular Ca(2+) handling contributes to both contractile dysfunction and arrhythmias in heart failure. Reduced Ca(2+) transient amplitude due to decreased sarcoplasmic reticulum Ca(2+) content is a common finding in heart failure models. However, heart failure models also show increased pro...

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Pubblicato in:PLoS One
Autori principali: Sadredini, Mani, Danielsen, Tore Kristian, Aronsen, Jan Magnus, Manotheepan, Ravinea, Hougen, Karina, Sjaastad, Ivar, Stokke, Mathis Korseberg
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838269/
https://ncbi.nlm.nih.gov/pubmed/27096943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153887
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