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TRIM5α is a SUMO substrate

BACKGROUND: The TRIM5α restriction factor interferes with retroviral infections by inhibiting an early step of viral replication. TRIM5α activity was recently proposed to be regulated by the SUMO machinery and one SUMO consensus conjugation site as well as three putative SUMO interacting motifs (SIM...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Dutrieux, Jacques, Portilho, Débora M, Arhel, Nathalie J, Hazan, Uriel, Nisole, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376147/
https://ncbi.nlm.nih.gov/pubmed/25880753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0155-7
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