A carregar...

RanBP2 regulates the anti-retroviral activity of TRIM5α by SUMOylation at a predicted phosphorylated SUMOylation motif

TRIM5α is a cytoplasmic restriction factor that blocks post-entry retroviral infection. Evidence suggests that its antiviral activity can be regulated by SUMO, but how this is achieved remains unknown. Here, we show that TRIM5α forms a complex with RanGAP1, Ubc9, and RanBP2 at the nuclear pore, and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Maarifi, Ghizlane, Fernandez, Juliette, Portilho, Débora M., Boulay, Aude, Dutrieux, Jacques, Oddos, Stéphane, Butler-Browne, Gillian, Nisole, Sébastien, Arhel, Nathalie J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237768/
https://ncbi.nlm.nih.gov/pubmed/30456314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0198-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!