RanBP2/Nup358 enhances miRNA activity by sumoylating Argonautes

Mutations in RanBP2 (also known as Nup358), one of the main components of the cytoplasmic filaments of the nuclear pore complex, contribute to the overproduction of acute necrotizing encephalopathy (ANE1)-associated cytokines. Here we report that RanBP2 represses the translation of the interleukin 6...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Shen, Qingtang, Wang, Yifan E., Truong, Mathew, Mahadevan, Kohila, Wu, Jingze J., Zhang, Hui, Li, Jiawei, Smith, Harrison W., Smibert, Craig A., Palazzo, Alexander F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924746/
https://ncbi.nlm.nih.gov/pubmed/33600493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009378
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