RanBP2/Nup358 enhances miRNA activity by sumoylating Argonautes

Mutations in RanBP2 (also known as Nup358), one of the main components of the cytoplasmic filaments of the nuclear pore complex, contribute to the overproduction of acute necrotizing encephalopathy (ANE1)-associated cytokines. Here we report that RanBP2 represses the translation of the interleukin 6...

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發表在:PLoS Genet
Main Authors: Shen, Qingtang, Wang, Yifan E., Truong, Mathew, Mahadevan, Kohila, Wu, Jingze J., Zhang, Hui, Li, Jiawei, Smith, Harrison W., Smibert, Craig A., Palazzo, Alexander F.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2021
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924746/
https://ncbi.nlm.nih.gov/pubmed/33600493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009378
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