Ran-dependent docking of importin-β to RanBP2/Nup358 filaments is essential for protein import and cell viability

RanBP2/Nup358, the major component of the cytoplasmic filaments of the nuclear pore complex (NPC), is essential for mouse embryogenesis and is implicated in both macromolecular transport and mitosis, but its specific molecular functions are unknown. Using RanBP2 conditional knockout mouse embryonic...

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Detalhes bibliográficos
Main Authors: Hamada, Masakazu, Haeger, Anna, Jeganathan, Karthik B., van Ree, Janine H., Malureanu, Liviu, Wälde, Sarah, Joseph, Jomon, Kehlenbach, Ralph H., van Deursen, Jan M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160583/
https://ncbi.nlm.nih.gov/pubmed/21859863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201102018
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