RanBP2/Nup358 enhances miRNA activity by sumoylating Argonautes

Mutations in RanBP2 (also known as Nup358), one of the main components of the cytoplasmic filaments of the nuclear pore complex, contribute to the overproduction of acute necrotizing encephalopathy (ANE1)-associated cytokines. Here we report that RanBP2 represses the translation of the interleukin 6...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Shen, Qingtang, Wang, Yifan E., Truong, Mathew, Mahadevan, Kohila, Wu, Jingze J., Zhang, Hui, Li, Jiawei, Smith, Harrison W., Smibert, Craig A., Palazzo, Alexander F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924746/
https://ncbi.nlm.nih.gov/pubmed/33600493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009378
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