RanBP2/Nup358 Potentiates the Translation of a Subset of mRNAs Encoding Secretory Proteins

In higher eukaryotes, most mRNAs that encode secreted or membrane-bound proteins contain elements that promote an alternative mRNA nuclear export (ALREX) pathway. Here we report that ALREX-promoting elements also potentiate translation in the presence of upstream nuclear factors. These RNA elements...

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Detalhes bibliográficos
Main Authors: Mahadevan, Kohila, Zhang, Hui, Akef, Abdalla, Cui, Xianying A., Gueroussov, Serge, Cenik, Can, Roth, Frederick P., Palazzo, Alexander F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635865/
https://ncbi.nlm.nih.gov/pubmed/23630457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001545
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