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Role of SUMO-1 and SUMO interacting motifs in rhesus TRIM5α-mediated restriction

BACKGROUND: TRIM5α is a member of the tripartite motif family of proteins that restricts retroviral infection in a species-specific manner. The restriction requires an interaction between the viral capsid lattice and the B30.2/SPRY domain of TRIM5α. Previously, we determined that two SUMO interactin...

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Detalhes bibliográficos
Main Authors: Lukic, Zana, Goff, Stephen P, Campbell, Edward M, Arriagada, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599732/
https://ncbi.nlm.nih.gov/pubmed/23369348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-10
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