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Contribution of SUMO-interacting motifs and SUMOylation to the antiretroviral properties of TRIM5α

Recent findings suggested that the SUMO-interacting motifs (SIMs) present in the human TRIM5α (TRIM5α(hu)) protein play an important role in the ability of TRIM5α(hu) to restrict N-MLV. Here we explored the role of SIMs in the ability of rhesus TRIM5α (TRIM5α(rh)) to restrict HIV-1, and found that T...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brandariz-Nuñez, Alberto, Roa, Amanda, Valle-Casuso, Jose Carlos, Biris, Nikolaos, Ivanov, Dmitri, Diaz-Griffero, Felipe
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534947/
https://ncbi.nlm.nih.gov/pubmed/23084420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.09.042
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