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Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner
Soluble karyopherins of the importin-β (impβ) family use RanGTP to transport cargos directionally through the nuclear pore complex (NPC). Whether impβ or RanGTP regulate the permeability of the NPC itself has been unknown. In this study, we identify a stable pool of impβ at the NPC. A subpopulation...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4375889/ https://ncbi.nlm.nih.gov/pubmed/25748139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04052 |
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