Ran-independent nuclear import of cyclin B1–Cdc2 by importin β
Mitosis is triggered in vertebrate cells by the cyclin B1–Cdc2 complex. The activation of this complex at the end of G(2) phase is accompanied by its translocation from the cytoplasm to the nucleus. We used digitonin-permeabilized human cells to analyze the mechanism by which cyclin B1–Cdc2 is impor...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22166/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10393926/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.14.7938 |
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