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Selectivity Mechanism of the Nuclear Pore Complex Characterized by Single Cargo Tracking

The Nuclear Pore Complex (NPC) mediates all exchange between the cytoplasm and the nucleus. Small molecules can passively diffuse through the NPC, while larger cargos require transport receptors to translocate1. How the NPC facilitates the translocation of transport receptor/cargo complexes remains...

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Main Authors: Lowe, Alan R., Siegel, Jake J., Kalab, Petr, Siu, Merek, Weis, Karsten, Liphardt, Jan T.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948059/
https://ncbi.nlm.nih.gov/pubmed/20811366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09285
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