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Single-molecule measurements of importin α/cargo complex dissociation at the nuclear pore

Macromolecules are transported between the cytoplasm and the nucleoplasm of eukaryotic cells through nuclear pore complexes (NPCs). Large (more than ≈40 kDa) transport cargoes imported into the nucleus typically form a complex with at least one soluble transport cofactor of the importin (Imp) β supe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sun, Changxia, Yang, Weidong, Tu, Li-Chun, Musser, Siegfried M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438397/
https://ncbi.nlm.nih.gov/pubmed/18562297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710867105
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