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Large cargo transport by nuclear pores: implications for the spatial organization of FG-nucleoporins

Nuclear pore complexes (NPCs) mediate cargo traffic between the nucleus and the cytoplasm of eukaryotic cells. Nuclear transport receptors (NTRs) carry cargos through NPCs by transiently binding to phenylalanine-glycine (FG) repeats on intrinsically disordered polypeptides decorating the NPCs. Major...

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Detalhes bibliográficos
Main Authors: Tu, Li-Chun, Fu, Guo, Zilman, Anton, Musser, Siegfried M
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981140/
https://ncbi.nlm.nih.gov/pubmed/24213245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.239
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