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Disorder in the nuclear pore complex: The FG repeat regions of nucleoporins are natively unfolded

Nuclear transport proceeds through nuclear pore complexes (NPCs) that are embedded in the nuclear envelope of eukaryotic cells. The Saccharomyces cerevisiae NPC is comprised of 30 nucleoporins (Nups), 13 of which contain phenylalanine-glycine repeats (FG Nups) that bind karyopherins and facilitate t...

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Autors principals: Denning, Daniel P., Patel, Samir S., Uversky, Vladimir, Fink, Anthony L., Rexach, Michael
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC151361/
https://ncbi.nlm.nih.gov/pubmed/12604785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437902100
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