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Disorder in the nuclear pore complex: The FG repeat regions of nucleoporins are natively unfolded

Nuclear transport proceeds through nuclear pore complexes (NPCs) that are embedded in the nuclear envelope of eukaryotic cells. The Saccharomyces cerevisiae NPC is comprised of 30 nucleoporins (Nups), 13 of which contain phenylalanine-glycine repeats (FG Nups) that bind karyopherins and facilitate t...

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Detalhes bibliográficos
Main Authors: Denning, Daniel P., Patel, Samir S., Uversky, Vladimir, Fink, Anthony L., Rexach, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151361/
https://ncbi.nlm.nih.gov/pubmed/12604785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437902100
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