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Disorder in the nuclear pore complex: The FG repeat regions of nucleoporins are natively unfolded

Nuclear transport proceeds through nuclear pore complexes (NPCs) that are embedded in the nuclear envelope of eukaryotic cells. The Saccharomyces cerevisiae NPC is comprised of 30 nucleoporins (Nups), 13 of which contain phenylalanine-glycine repeats (FG Nups) that bind karyopherins and facilitate t...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Denning, Daniel P., Patel, Samir S., Uversky, Vladimir, Fink, Anthony L., Rexach, Michael
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12604785/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437902100
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