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Novel Roles of c-Met in the Survival of Renal Cancer Cells through the Regulation of HO-1 and PD-L1 Expression

The receptor tyrosine kinase c-Met is overexpressed in renal cancer cells and can play major role in the growth and survival of tumor. We investigated how the c-Met-mediated signaling through binding to its ligand hepatocyte growth factor (HGF) can modulate the apoptosis and immune escape mechanism(...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Balan, Murugabaskar, Mier y Teran, Eduardo, Waaga-Gasser, Ana Maria, Gasser, Martin, Choueiri, Toni K., Freeman, Gordon, Pal, Soumitro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375468/
https://ncbi.nlm.nih.gov/pubmed/25645920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.612689
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