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The Heme Oxygenase-1 Protein Is Overexpressed in Human Renal Cancer Cells following Activation of the Ras-Raf-ERK Pathway and Mediates Anti-Apoptotic Signal

The stress-inducible cytoprotective enzyme heme oxygenase-1 (HO-1) may play a critical role in the growth and metastasis of tumors. We demonstrated that overexpressed HO-1 promotes the survival of renal cancer cells by inhibiting cellular apoptosis; we also showed that the proto-oncogene H-Ras becom...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Banerjee, Pallavi, Basu, Aninda, Datta, Dipak, Gasser, Martin, Waaga-Gasser, Ana Maria, Pal, Soumitro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190937/
https://ncbi.nlm.nih.gov/pubmed/21808062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.248401
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