CXCR3-B Can Mediate Growth-inhibitory Signals in Human Renal Cancer Cells by Down-regulating the Expression of Heme Oxygenase-1

The chemokine receptor CXCR3 may play a critical role in the growth and metastasis of tumor cells, including renal tumors. It has been shown that CXCR3 has two splice variants with completely opposite functions; CXCR3-A promotes cell proliferation, whereas CXCR3-B inhibits cell growth. We recently d...

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Hlavní autoři: Datta, Dipak, Banerjee, Pallavi, Gasser, Martin, Waaga-Gasser, Ana Maria, Pal, Soumitro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978613/
https://ncbi.nlm.nih.gov/pubmed/20855888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.170324
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