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Heme Oxygenase-1 Promotes Survival of Renal Cancer Cells through Modulation of Apoptosis- and Autophagy-regulating Molecules

The cytoprotective enzyme heme oxygenase-1 (HO-1) is often overexpressed in different types of cancers and promotes cancer progression. We have recently shown that the Ras-Raf-ERK pathway induces HO-1 to promote survival of renal cancer cells. Here, we examined the possible mechanisms underlying HO-...

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Detalhes bibliográficos
Main Authors: Banerjee, Pallavi, Basu, Aninda, Wegiel, Barbara, Otterbein, Leo E., Mizumura, Kenji, Gasser, Martin, Waaga-Gasser, Ana Maria, Choi, Augustine M., Pal, Soumitro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442542/
https://ncbi.nlm.nih.gov/pubmed/22843690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.393140
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