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Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine

Recovery from encephalomyelitis induced by infection with mosquito-borne alphaviruses is associated with a high risk of lifelong debilitating neurological deficits. Infection of mice with the prototypic alphavirus, Sindbis virus, provides an animal model with which to study disease mechanisms and ex...

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Détails bibliographiques
Publié dans:J Neurovirol
Auteurs principaux: Potter, Michelle C., Baxter, Victoria K., Mathey, Robert W., Alt, Jesse, Rojas, Camilo, Griffin, Diane E., Slusher, Barbara S.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375032/
https://ncbi.nlm.nih.gov/pubmed/25645378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-015-0314-6
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