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Bioanalysis of 6-Diazo-5-oxo-L-norleucine (DON) in plasma and brain by ultra-performance liquid chromatography mass spectrometry

Glutamine is an abundant amino acid that plays pivotal roles in cell growth, cell metabolism and neurotransmission. Dysregulation of glutamine-utilizing pathways has been associated with pathological conditions such as cancer and neurodegenerative diseases. 6-Diazo-5-Oxo-L-Norleucine (DON) is a reac...

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Detalhes bibliográficos
Publicado no:Anal Biochem
Main Authors: Alt, Jesse, Potter, Michelle C., Rojas, Camilo, Slusher, Barbara S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357560/
https://ncbi.nlm.nih.gov/pubmed/25584882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.01.001
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