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Isoflurane Postconditioning Protects Against Reperfusion Injury by Preventing Mitochondrial Permeability Transition via an Endothelial Nitric Oxide Synthase-dependent Mechanism
BACKGROUND: The role of endothelial nitric oxide synthase (eNOS) in isoflurane postconditioning (IsoPC)-elicited cardioprotection is poorly understood. We addressed this issue using eNOS(-/-) mice. METHODS: In vivo or Langendorff-perfused mouse hearts underwent 30 min of ischemia followed by 2 h of...
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| Veröffentlicht in: | Anesthesiology |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374483/ https://ncbi.nlm.nih.gov/pubmed/19996950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181c4a607 |
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