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Complex I and ATP synthase mediate membrane depolarization and matrix acidification by isoflurane in mitochondria

Short application of the volatile anesthetic isoflurane at reperfusion after ischemia exerts strong protection of the heart against injury. Mild depolarization and acidification of the mitochondrial matrix are involved in the protective mechanisms of isoflurane, but the molecular basis for these cha...

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Sonraí Bibleagrafaíochta
Main Authors: Pravdic, Danijel, Hirata, Naoyuki, Baber, Lauren, Sedlic, Filip, Bosnjak, Zeljko J., Bienengraeber, Martin
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653412/
https://ncbi.nlm.nih.gov/pubmed/22796646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.07.003
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