Complex I and ATP synthase mediate membrane depolarization and matrix acidification by isoflurane in mitochondria

Short application of the volatile anesthetic isoflurane at reperfusion after ischemia exerts strong protection of the heart against injury. Mild depolarization and acidification of the mitochondrial matrix are involved in the protective mechanisms of isoflurane, but the molecular basis for these cha...

Full description

Saved in:
Bibliographic Details
Main Authors: Pravdic, Danijel, Hirata, Naoyuki, Baber, Lauren, Sedlic, Filip, Bosnjak, Zeljko J., Bienengraeber, Martin
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653412/
https://ncbi.nlm.nih.gov/pubmed/22796646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.07.003
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items