Anesthetic-induced preconditioning delays opening of mitochondrial permeability transition pore via protein kinase C-ε mediated pathway

BACKGROUND: Cardioprotection by volatile anesthetic-induced preconditioning (APC) involves activation of protein kinase C (PKC). The current study investigated the importance of APC-activated PKC in delaying mitochondrial permeability transition pore (mPTP) opening. METHODS: Rat ventricular myocytes...

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Autores principales: Pravdic, Danijel, Sedlic, Filip, Mio, Yasushi, Vladic, Nikolina, Bienengraeber, Martin, Bosnjak, Zeljko J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744603/
https://ncbi.nlm.nih.gov/pubmed/19568162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181a91957
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