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SNES: single nucleus exome sequencing

Single-cell genome sequencing methods are challenged by poor physical coverage and high error rates, making it difficult to distinguish real biological variants from technical artifacts. To address this problem, we developed a method called SNES that combines flow-sorting of single G1/0 or G2/M nucl...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Leung, Marco L, Wang, Yong, Waters, Jill, Navin, Nicholas E
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373516/
https://ncbi.nlm.nih.gov/pubmed/25853327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0616-2
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