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SNES: single nucleus exome sequencing

Single-cell genome sequencing methods are challenged by poor physical coverage and high error rates, making it difficult to distinguish real biological variants from technical artifacts. To address this problem, we developed a method called SNES that combines flow-sorting of single G1/0 or G2/M nucl...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Biol
Hauptverfasser: Leung, Marco L, Wang, Yong, Waters, Jill, Navin, Nicholas E
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373516/
https://ncbi.nlm.nih.gov/pubmed/25853327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0616-2
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