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Highly multiplexed targeted DNA sequencing from single nuclei
Single-cell DNA sequencing methods are challenged by poor physical coverage, high technical error rates and low throughput. To address these issues, we developed a single-cell DNA sequencing protocol that combines flow-sorting of single nuclei, time-limited multiple-displacement amplification (MDA),...
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| Veröffentlicht in: | Nat Protoc |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807405/ https://ncbi.nlm.nih.gov/pubmed/26741407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.005 |
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