Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer

Single cell RNA sequencing has emerged as a powerful tool for resolving transcriptional diversity in tumors, but is limited by throughput, cost and the ability to process archival frozen tissue samples. Here we develop a high-throughput 3′ single-nucleus RNA sequencing approach that combines nanogri...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gao, Ruli, Kim, Charissa, Sei, Emi, Foukakis, Theodoros, Crosetto, Nicola, Chan, Leong-Keat, Srinivasan, Maithreyan, Zhang, Hong, Meric-Bernstam, Funda, Navin, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550415/
https://ncbi.nlm.nih.gov/pubmed/28794488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00244-w
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